Assistant Professor Dr Yassir Abdel-Kazim a teaching staff at the College of Dentistry/ University of Baghdad, and MSc. student Rawof R Al Tuma published scientific research in Scopus Q1 journal.
The research entitled ‘’Effect of calcium fluoride nanoparticles in prevention of demineralization during orthodontic fixed appliance treatment: a randomized clinical trial’’. The study aimed to evaluate the effectiveness of calcium fluoride nanoparticles-containing orthodontic primer (nCaF2-primer) in preventing the incidence of WSLs during orthodontic treatment.
A new orthodontic adhesive primer with a concentration of 20% calcium fluoride nanoparticles (nCaF2-primer) was selected to be evaluated in a randomized clinical trial. The sample included 31 orthodontic patients. The patients were involved using randomization. Outcome measures included comparing the effect of orthodontic nCaF2-primer containing calcium fluoride nanoparticles with the orthodontic adhesive primer named (Transbond XT™) regarding the degree of demineralization (DIAGNOdent pen), Streptococcus mutans (S. mutans) bacterial counting [real-time polymerase chain reaction device (PCR)], and WSLs incidence (pre- and post-operative photographs).
nCaF2-primer effectively decreased demineralization scores within the 6 months after bracket bonding. Moreover, it significantly reduced S. mutans colonization after the first month. However, the tested primer did not have an extra advantage in preventing WSLs development at the clinical level after appliance removal.

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