The research entitled (Evaluation of biomarkers of NETosis in smokers and non-smokers with periodontitis) was published by researchers Prof. Dr. Batool Hassan Hashim and master’s student Rasha Abdul Jabbar Najm. at the College of Dentistry, University of Baghdad, Department of Basic Sciences in the journal F1000Research
in the United Kingdom. The journal issued by Taylor & Francis.
The aim of the study: To evaluate the salivary levels of biomarkers of NETosis (citrullinated histone-3, neutrophil elastase, calprotectin and myeloperoxidase) as indicators of inflammation in patients with severe periodontitis (smokers and non-smokers), and to determine the relationship between NETosis biomarkers and clinical periodontal signs.
The study included: Enrolling 85 patients in this study and the participants were divided into three groups as follows: healthy people and periodontal patients from smokers and non-smokers.
The study recommended: The selected salivary biomarkers revealed high clinical accuracy in distinguishing between the gingivitis groups taken into the study (smokers and non-smokers) from the control group. The study also noted that cigarette smoking can increase the risk of gingivitis, and neutrophils in smokers showed a greater ability to form neutrophil extracellular traps compared to non-smokers.
Research link
https://doi.org/10.12688/f1000research.152917.1
