The research titled “Green synthesis of gold nanoparticles using Pelargonium Graveolens leaf extract: characterization and anti-microbial properties (An in-vitro study)” was published by Assist. Prof. Asil Haider Mohammed Jawad, Head of the Department of Pediatric and Preventive Dentistry, and Master’s student Ahmed Yousif Mahdi Askar, from the College of Dentistry, University of Baghdad, Department of Pediatric and Preventive Dentistry, in F1000Research journal in the United Kingdom.
The aim of the study was to establish a nanoplatform with the potential to be environmentally sustainable, while also demonstrating exceptional antimicrobial properties against Streptococcus mutans and Candida albicans.
The study involved the use of Pelargonium Graveolens leaf extract as a cost-effective and eco-friendly approach for the green synthesis of AuNPs (gold nanoparticles). The physical and chemical properties were evaluated using a variety of analytical methods, including transmission electron microscopy (TEM), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), UV-Vis spectroscopy, energy-dispersive X-ray spectroscopy (EDX), and Fourier-transform infrared spectroscopy (FTIR). The antimicrobial efficacy was assessed against Streptococcus mutans and Candida albicans.
The synthesized nanoparticles exhibited diverse shapes, including hexagonal, spherical, quasi-spherical, and triangular forms. They showed an average particle size of 294 nm, low aggregation, long-term stability, and the ability to easily integrate with various biologically active compounds.
The study recommended the use of gold nanoparticles synthesized from Pelargonium Graveolens (AuNPs), which demonstrated promising potential as antibacterial agents against Streptococcus mutans and Candida albicans. These nanoparticles (NPs) have the capacity to serve as a novel approach for combating pathogenic infections, as well as for future biomedical, dental, and pharmaceutical applications.
